Pharmacology MCQs

Q- A patient treated with a nonselective beta blocker develops hypoglycemia that is difficult to recognize. What explains the masking of hypoglycemia symptoms? A- Alpha receptor blockade B- Beta-1 receptor stimulation C- Beta-2 receptor blockade D- Muscarinic receptor blockade   Q- A patient with hyperlipidemia is treated with cholestyramine. What is the primary mechanism by … Read more

Q- A patient receiving trimethoprim-sulfamethoxazole develops megaloblastic anemia. Which mechanism explains this adverse effect? A- Folate metabolism inhibition B- Hemoglobin oxidation C- Inhibition of erythropoietin synthesis D- Vitamin B12 malabsorption   Q- A patient with hypertension is treated with clonidine. What is the primary mechanism by which this drug lowers blood pressure? A- Alpha-1 receptor … Read more

Q- A patient treated with vancomycin develops acute kidney injury. Which concurrent medication increases this risk most significantly? A- Amoxicillin B- Azithromycin C- Gentamicin D- Metronidazole   Q- A patient who is taking a high dose of niacin for hyperlipidemia develops hyperglycemia. What explains this effect? A- Decreased insulin secretion B- Decreased peripheral glucose uptake … Read more

Q- A patient with heart failure is started on sacubitril/valsartan. What is the primary pharmacologic action of sacubitril? A- Angiotensin II receptor blockade B- Inhibition of neprilysin C- Inhibition of renin release D- Stimulation of natriuretic peptide receptors   Q- A patient taking linezolid develops thrombocytopenia after prolonged therapy. What is the underlying mechanism? A- … Read more

Q- A patient taking warfarin is given vitamin K. What is the primary effect of vitamin K administration? A- Decreases synthesis of clotting factors II, VII, IX, X B- Increases synthesis of clotting factors II, VII, IX, X C- Inhibits platelet aggregation D- Prevents fibrin degradation   Q- A patient taking spironolactone develops breast enlargement … Read more