Repeated USMLE Questions Step 2 CK- Review- 52

Q- A 67-year-old man presents with sudden onset left arm weakness and facial droop that resolved completely within 30 minutes. CT scan of the head is normal. What is the most likely diagnosis? A- Intracerebral hemorrhage B- Ischemic stroke C- Subarachnoid hemorrhage D- Transient ischemic attack   Q- A 34-year-old woman presents with heat intolerance, … Read more

Repeated USMLE Questions Step 1 Review-157- Pharmacology

Q- A patient treated with cisplatin develops hearing loss. What is the mechanism of this adverse effect? A- Accumulation in cochlear hair cells B- Autoimmune inner ear inflammation C- Decreased cerebral perfusion D- Inhibition of prostaglandin synthesis   Q- A patient taking phenelzine develops severe hypertension after eating aged cheese. What is the underlying cause … Read more

Repeated USMLE Questions Step 1- Review- 156

Q- A 6-month-old infant presents with recurrent bacterial and fungal infections. Laboratory testing shows markedly decreased CD18 expression on neutrophils. Which of the following mechanisms is primarily impaired? A- Chemotaxis toward IL-8 B- Diapedesis through endothelium C- Phagolysosome fusion D- Reactive oxygen species formation   Q- A patient with chronic alcoholism develops confusion, ophthalmoplegia, and … Read more

Repeated USMLE Questions Step 1 Review-155- Pharmacology

Q- A patient treated with gentamicin develops renal impairment. What is the primary mechanism of this adverse effect? A- Accumulation in proximal tubule cells B- Acute interstitial nephritis C- Decreased renal blood flow D- Immune-mediated glomerulonephritis   Q- A patient on long-term NSAID therapy develops gastric ulcers. Which mechanism is responsible? A- Decreased leukotriene production … Read more

Repeated USMLE Questions Step 1 Review-153- Pharmacology

Q- Which of the following antifungal medications inhibits ergosterol synthesis by blocking fungal cytochrome P450 enzymes? A- Amphotericin B B- Fluconazole C- Flucytosine D- Terbinafine   Q- A 29-year-old woman treated with lithium presents with tremor, polyuria, and confusion. Which laboratory finding is most likely present? A- Hypercalcemia B- Hypoglycemia C- Hypokalemia D- Hyponatremia   … Read more

Repeated USMLE Questions Step 1- Review- 152

Q- A 65-year-old man with heart failure is started on spironolactone. Which adverse effect should be monitored most closely? A- Gynecomastia B- Hypocalcemia C- Hypokalemia D- Metabolic acidosis   Q- A 60-year-old man presents with weakness, fatigue, and splenomegaly. His complete blood count shows pancytopenia. Bone marrow aspiration is “dry,” but biopsy shows fibrotic marrow … Read more