Q- Which one of the following drugs is most likely to cause severe bone marrow depression?
A- Cyclosporine
B- Prednisone
C- Sirolimus
D- Tacrolimus
Q- Which one of the following defines the drug efficacy?
A- The capacity of a drug to affect a condition, irrespective of the dose
B- The dose of a drug needed to produce a maximal effect
C- The impact of the drug on a wide range of patients
D- The minimal amount of drug administered that leads to toxicity
Q- Which one of the following indicates drug resistance?
A- Altered effect of the drug when used with another drug
B- Induction of liver metabolism
C- No or minimum effect on a microorganism due to genetic mutation
D- Response to a drug decreases after repeated use
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Hi Dr. Adaba, side effects do not affect the efficacy of the drug.
Efficacy is defined as the maximum therapeutic effect a drug can achieve when it fully activates its target receptors. It’s purely about how much benefit the drug can produce.
Side effects are unwanted effects that occur when a drug acts on other receptors, tissues, or pathways, or when it excessively activates the same receptor in unintended places.
I wish this answered your question. Please let me know if you require further clarification. Thank you
The capacity of a drug to affect a condition irrespective of the dose. Can you explain more on this answer. Are you taking into consideration the adverse effects of the drug with respect to the dose.
Very helpful revision questions. Much thanks Dr ray makar