Free Questions and Answers for All Medical Students all over the World
Q- A patient treated with tacrolimus after kidney transplantation develops nephrotoxicity. What is the primary molecular mechanism of tacrolimus? A- Blocks IL-2 transcription by inhibiting calcineurin B- Inhibits dihydrofolate reductase C- Inhibits inosine monophosphate dehydrogenase D- Stimulates T-cell apoptosis directly Q- A patient with chronic angina is treated with ranolazine. What is the primary … Read more
Q- A drug that increases GABA activity in the central nervous system is prescribed for anxiety. Which class of drugs acts by increasing the frequency of chloride channel opening at the GABA-A receptor? A- Barbiturates B- Benzodiazepines C- Selective serotonin reuptake inhibitors D- Tricyclic antidepressants Q- A woman has heavy menstrual bleeding and prolonged … Read more
Q- A patient with atrial fibrillation is treated with dofetilide. Which electrophysiologic effect explains the antiarrhythmic action of this drug? A- Decreased phase 0 depolarization B- Increased refractory period by potassium channel blockade C- Inhibition of calcium influx in AV node D- Sodium channel blockade during depolarization Q- A patient treated with acetazolamide develops … Read more
Q- A 64-year-old man with a long history of smoking presents with hematuria. Cystoscopy reveals a papillary tumor arising from the bladder mucosa. Which molecular alteration is most commonly associated with low-grade papillary urothelial carcinoma? A- KRAS mutation B- FGFR3 mutation C- BRAF mutation D- APC mutation Q- A 14-year-old boy presents with a … Read more
Q- A patient with Parkinson’s disease is treated with selegiline. What is the primary mechanism of this drug? A- Inhibition of catechol-O-methyltransferase B- Inhibition of monoamine oxidase B C- Stimulation of dopamine receptors D- Stimulation of muscarinic receptors Q- A patient treated with verapamil develops constipation and bradycardia. What class of drug does verapamil … Read more
Q- A child has chronic diarrhea and failure to thrive. Stool is positive for fat. The sweat chloride test is elevated. Which mechanism explains the GI symptoms? A- Decreased pancreatic enzyme secretion B- Increased bile acid synthesis C- Increased gastric acid production D- Increased intestinal chloride secretion Q- A patient has progressive weakness and … Read more