A 1-year-old girl is brought to the pediatrician by her parents due to poor growth and skeletal abnormalities. Laboratory investigations show microcytic anemia and higher concentration of hemoglobin A2. Which is the most likely diagnosis? A- Sickle cell anemia B- β-thalassemia C- Lead poisoning D- Iron deficiency Answer β-thalassemia is an inherited blood disorder that […]
usmle
Repeated USMLE Questions Step 1-302
A 60-year-old man visits the clinic due to profuse watery diarrhea and left lower abdominal colicky pain for the last 6 hours. Upon taking history, the patient claims that he is taking broad spectrum antibiotics for acute bronchitis. Which is the most likely causative organism for the patient’s new symptoms? A- Clostridium botulinum B- Clostridium […]
Repeated USMLE Questions Step 1- 301
A 52-year-old man who is recently diagnosed with gout is presented to his physician to discuss his treatment plan. One of the treatments that will be taken is allopurinol. Which of these enzymes is targeted by this medication? A-Hypoxanthine guanine phosphoribosyltransferase B-Phosphoribosylpyrophosphate synthase C-Guanase D-Xanthine oxidase Answer Allopurinol is used to treat chronic gout due […]
Repeated USMLE Questions Step 1- 300
A 45-year-old woman working as a secretary visits her physician complaining of tingling and numbness in her hands. Upon conducting a physical examination, the doctor finds that the patient also has decreased sensation in all her fingers, except for the fifth digit. Keeping these in mind, which of the following muscles is usually weakened in […]
Repeated USMLE Questions Step 1- 298
A 56-year-old man presents to the clinic due to recurrent attacks of severe pain in his right big toe for the last few weeks. During the attacks, his toe becomes painful, red, warm and swollen. Significant improvement occurs after treatment with colchicine. Synovial fluid analysis is performed to confirm the diagnosis. What is the most […]
Repeated USMLE Questions Step 1- 297
A 4-year-old boy visits you in the clinic with his mother for evaluation of an increasing size of his genitalia. She tells you that her boy had aggressive behavior for the last six months. Besides progressive increase of the length of his penis, he has excessive pubic hair. On examination, his pulse is 80/min. and […]