Free Questions and Answers for All Medical Students all over the World
Free USMLE Step 1 practice questions covering pharmacology, pathology, biochemistry, physiology, immunology, microbiology and genetics. Many are repeated, high-yield question types that students report seeing on the real exam.
Study by subject
Use the Subjects menu to practice one topic at a time, such as pharmacology, pathology, cardiology or hematology, or work through the review sets below for mixed practice like the real exam.
Try each question before opening the answer, then read the explanation even when you get it right. Each post has 3–8 exam-style questions with answers and short explanations written by Dr. Ray Makar.
Want hundreds more? See the Repeated USMLE Questions eBook series on Amazon.
Q- Which of the following antibiotics is the most appropriate one to treat a case of Legionella pneumonia? A- Clindamycin B- Ciprofloxacin C- Metronidazole D- Vancomycin Q- Which of the following medications should be given to a patient who exhibits severe adverse reactions after administration of IV midazolam? A- Flumazenil B- Glucagon C- Naloxone D- … Read more
Q- A 2-week-old boy is brought for persistent vomiting of non-bilious material after feeding. The boy is lysergic and dehydrated. Examination reveals presence of an olive-sized mass in the epigastric area moving with peristalsis. What is the most likely diagnosis? A- Duodenal atresia B- Esophageal atresia C- Meckel’s diverticulum D- Pyloric stenosis Q- Which of … Read more
Q- A 56-year-old woman is found to have elevated intraocular pressure during a routine eye examination. Examination also reveals normal optic disc and open angle of the eye. Her doctor explains to her that her condition is probably due to increased secretion of aqueous fluid. This fluid is produced by which of the following structures? … Read more
Q- A 5-year-old boy is brought to the emergency room for a cough and trouble breathing. His parents mentioned that he was playing with some coins a short time ago. The coin is most likely lodged in which of the following lobar bronchi? A- Left middle lobar bronchus B- Left superior lobar bronchus C- Right … Read more
A 30-year-old man presents to the emergency room with excruciating chest pain and shortness of breath for an hour. Past, surgical and familial histories are unremarkable except that his father died of a heart attack at the age of 32. Imaging studies and laboratory tests confirm the diagnosis of myocardial infarction. What is the most … Read more
Q- Which of the following is most likely characteristic of the oral route of administration? A- Absorption of the drug depends on the GIT function B- It has the fastest onset of effect C- It is the most appropriate route to interact with most of the emergencies D- Most oral medications reach the bloodstream through … Read more